By 2026, 5G will be deployed in almost every region to boost connectivity performance, drive innovation, and unleash tremendous business opportunities by developing new consumer’s experiences and new industrial uses cases like advanced automation to tackle Industry 4.0 or deploy massively IoT in a Smart city. The combination of 5G with AI, VR/AR/XR will probably transform our digital experience and bring it to another level, and even change our way to learn and to behave as citizen. In countries with full 5G implementation, the first use of augmented and virtual reality (AR/VR) technology applied in holographic communication tools could be within the next year. According to Grand View Research, the global 5G services market size was valued at USD 41.48 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 46.2% from 2021 to 2028 In this conference, we would like to develop around the latest innovations making 5G and beyond (LPWA, hybrid networks) more performant and affordable as well as an outlook of the latest successful use cases for verticals deployment and specifically in massive IoT ecosystem.